The importance of sleep for brain health: How does the brain's nighttime cleansing system work?

In modern medical understanding, sleep is no longer merely a state of physical inactivity or passive rest, but rather a highly complex and active biological process that forms the cornerstone of maintaining mental and physical health. In this context, Dr. Diaa Hussein, a rheumatologist and osteoporosis specialist, emphasized in statements to Al-Youm newspaper that sleep is the fundamental pillar for sustaining vital brain functions. He warned that the silent depletion caused by sleep deprivation can lead to serious consequences that extend beyond mental impairment to include cardiovascular health.
The evolution of the medical concept of sleep
The importance of sleep transcends historical understanding. While it was once viewed as a temporary hiatus of consciousness, advanced scientific research in recent decades has demonstrated that the brain is at its peak activity during deep sleep. This shift in scientific understanding highlights the importance of sleep as a vital "nighttime maintenance" process, during which the body repairs damaged cells, regulates hormones, and processes information acquired during the day. This explains why good sleep is considered a fundamental indicator of overall health and quality of life.
Brain cleansing mechanism: How does the brain get rid of its toxins?
Dr. Diaa explained that the relationship between sleep and brain health is direct and direct; good sleep activates a precise system for cleansing the brain of protein waste and neurotoxins that accumulate during waking hours as a result of metabolic processes. He pointed out that cerebrospinal fluid plays the role of a "cleaning agent," moving in a rhythmic pattern synchronized with brain waves during sleep to cleanse brain tissue.
He added that recent studies have proven that sleep deprivation disrupts this mechanism, leading to the accumulation of harmful proteins linked to neurodegenerative diseases such as Alzheimer's. When the brain attempts to compensate for this deficiency during wakefulness, a phenomenon known as "attention deficit" occurs, causing cerebrospinal fluid to leak out of the brain and slowing down the body's vital responses. This explains the poor concentration and slow reaction times experienced by stressed individuals.
Global studies: Sleep and brain aging
Dr. Diaa cited a number of international studies that confirm these facts, most notably:
- A study by Sweden’s Karolinska Institute revealed that poor sleep quality accelerates brain aging, with MRI scans showing that the brains of people with insomnia appear older than their actual age, indicating early cognitive decline.
- Research from the University of Toronto in Canada has linked interrupted sleep to damage to the tiny blood vessels in the brain, which directly increases the risk of dementia and strokes.
- British studies on heart health have broadened the scope of risks to include the heart, with researchers finding that irregular sleep and wake times increase the risk of heart attacks and strokes by up to 26%.
The social and economic impact of sleep
The impact of sleep disorders extends far beyond the individual, encompassing broad economic and social consequences. Reduced productivity, increased traffic and workplace accidents, and declining academic performance are all direct results of insufficient sleep. Experts suggest that promoting a culture of healthy sleep can help alleviate the burden on healthcare systems and improve the overall efficiency of society.
Medical tips to boost brain health
Dr. Diaa concluded his remarks by offering a set of medical recommendations to ensure quality sleep, emphasizing that sleep is not a luxury but a biological necessity. His advice included:
- Adhering to a regular sleep and wake schedule, even on weekends, is essential for adjusting the biological clock.
- Refrain from using electronic devices at least one hour before bedtime to avoid the effect of blue light on the melatonin hormone.
- Creating an ideal sleeping environment characterized by tranquility and complete darkness.
- Engage in physical activity during the day and avoid stimulants and heavy meals at night.



