95% of your happiness hormone is in your gut: The link between the digestive system and mood

In a medical discovery that challenges conventional notions about mental and physical health, Dr. Tarek El-Shaarawy, a consultant in gastroenterology and hepatology, confirmed a surprising scientific fact concerning the "happiness hormone," or serotonin. Contrary to the common belief that the brain is the primary producer of this neurotransmitter responsible for regulating mood, it has been shown that 95% of this vital substance is produced within the digestive system.
The Second Brain: A New Scientific Context
These statements reinforce the concept of the "second brain," which has been gaining traction in medical circles in recent decades. Historically, the focus has been solely on the central nervous system as being responsible for psychological state. However, recent studies in neurogastroenterology have demonstrated that the gut possesses a complex neural network that operates independently and communicates with the brain. Dr. Al-Shaarawi explained to Al-Youm that specialized enterochromaffin cells in the intestinal lining are the true factory of serotonin, releasing it in response to various dietary and neurological stimuli.
Vital functions that go beyond mood
The role of gut serotonin is not limited to improving mood, but it also plays the role of "maestro" in physiological processes:
- Regulation of movement: It controls the contractions of smooth muscles to ensure peristaltic bowel movement and smooth digestion.
- Weight control: It sends "satiety" signals to the brain, making it a key focus in obesity treatment and appetite control research.
- Body defense: When exposed to poisoning or irritation, the intestines pump out large amounts of it to stimulate nausea or diarrhea to expel toxins quickly.
The gut-brain axis and its health impact
The consultant addressed the importance of the "gut-brain axis," noting that serotonin acts as a form of communication between the two systems via the vagus nerve. This close connection explains the reciprocal influence; psychological stress leads to digestive disorders, and conversely, indigestion and an imbalanced gut microbiome affect mental health. This opens up broad avenues for treating depression and anxiety through nutrition and gut health.
Therapeutic applications and preventative advice
Dr. El-Shaarawy pointed out that understanding the mechanism of serotonin's action explains the symptoms of irritable bowel syndrome (IBS), as well as the side effects of chemotherapy such as nausea, paving the way for the development of more precise medications. To naturally boost the production of this "happiness hormone," the doctor advised focusing on foods rich in tryptophan, such as eggs, spinach, and poultry, emphasizing that a balanced diet and exercise are key to holistic mental and physical health.



